Diagnosis & Management:
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Donovanosis contents
Illustrated
lecture transcript
Diagnosis and
management
Essential facts
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Donovanosis
Diagnosis
Clinical
Infection
occurs predominantly in Aborigines and occasionally in non-Aborigines who
have had sex with Aborigines. Typical granulomatous lesions are beefy red
and painless.
Laboratory
A
biopsy specimen is crushed against a slide which is air-dried and stained
with Wright's or Giemsa's stain. PCR
testing is available in specialised laboratories.
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| These photographs illustrate the typical
red beefy granulomatous nature of most donovanosis lesions. More
pictures available in the illustrated lecture
transcript. |
Treatment
All antibiotics should be taken until lesions heal
Standard therapy
azithromycin 1 gm orally weekly
(ADEC
B1)
or
doxycycline 100 mg orally 12
hourly (ADEC D)
after failed therapy, or for immunosuppressed patients
azithromycin 500 mg orally daily (ADEC
B1)
Patient education & contact tracing
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